Hyperbaric Oxygen Review,
Undersea Medical Society, Inc.
October 1982,
Volume 3, Number 4
Plenum press - New York and London
HOXRD6 3(4) 193-256 (1982)
ISSN 0195-9263
Page 226
Other Applications: Pregnancy and Neonates Baiborodov, B.D.
Some Peculiarities in Application of Hyperbaric Oxygenation During the
Treatment of Acute Respiratory Insufficiency in Newborn Infants.
In: Abstracts VII Int. Cong. HBO Medicine, Moscow, Sept. 2-6, 1981; p368.
HBO was used in 830 newborn infants: in 555 infants with asphyxia, in 165
infants with syndrome of respiratory disturbances (SRD) and 110 infants with
the aspiratory syndrome (AS). During the treatment of asphyxia an early use
of HBO, 1-5 min after artificial pulmonary ventilation (APV), as compared
with a late use of HBO, 10-30 min after APV, leads to a decrease of cerebral
circulatory disorders by 4 time a, and or mortality rate by 8 times. During
the treatment of SRD, the employment of HBO in the First 1-3 hrs of life led
to recovery of 75% of infants. The delayed use of HBO, 12-48 hrs after birth
is ineffective. HBO applied in the first hour of life during the treatment
of AS prevented the development of aspiratory pneumonia in 92.7% of cases.
HBO should be used during the treatment of neonatal asphyxia in combination
with APV, infusion "alkalizing" therapy, and during the treatment of SRD and
AS it should be combined with cardial, anti-bacterial, infusion,
"alkalizing" therapy. The duration of sessions should not be less than 1.5-2
hrs and not more than 3 hrs at 2-3 ATA for 10-15 min and at 1.4-1.5 ATA for
1.5-2.5 hrs. When these conditions are met acid-base balance and blood gases
normalize. If necessary, such sessions are repeated in 6-9 hors; to delay
them for 12-30 hors is not advisable. Thus, effectiveness of HBO during the
treatment of acute hypoxic states in new-born infants depends on its early,
complex and repeated application under safe resuscitation and therapeutic
regimes.
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