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Neurology 1997 Dec;49(6):1621-30
Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study

The North America ALS/IGF-I Study Group.

Lai EC, Felice KJ, Festoff BW, Gawel MJ, Gelinas DF, Kratz R, Murphy MF, Natter HM, Norris FH, Rudnicki SA.

Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA.

Recombinant human insulin-like growth factor-I slowed the progression of functional impairment and the decline in health-related quality of life in patients with ALS with no medically important adverse effects.

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