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Perinatal/Neonatal Case Presentation
Journal of Perinatology (2006) 26, 777–779. doi:10.1038/sj.jp.7211606

Hyperbaric oxygen in treatment of neonatal arterial thromboembolism of lower extremities J Wiebers1, I Purdy1, M Lieber2 and V Milisavljevic1

1. Division of Neonatology & Developmental Biology, Department of Pediatrics, University of California Los Angeles, Los Angeles, CA, USA

2. Gonda Center for Wound Healing & Hyperbaric Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA

Correspondence: Dr V Milisavljevic, Division of Neonatology & Developmental Biology, Department of Pediatrics, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Room B2-375 MDCC, Los Angeles, CA 90095, USA. E-mail: vmilisavljevic@mednet.ucla.edu

Received 5 November 2006; Revised 17 August 2006; Accepted 8 September 2006.

Abstract

Arterial thromboembolism (TE) in the absence of current or recent history of a central catheter is a rare condition in newborn period. We report a case of severe lower extremities arterial TE of unclear etiology in a full-term neonate. By adding hyperbaric oxygenation to thrombolytic and antithrombotic therapy, we achieved improved perfusion of the upper leg tissues, preserving the knee and enabling below-the-knee amputation.

Keywords:

hyperbaric oxygen, thromboembolism in newborn

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